Modulation of muscle fuel metabolism in human volunteers by increasing the availability of muscle acetyl-CoA and carnitine moieties

QR Code

Modulation of muscle fuel metabolism in human volunteers by increasing the availability of muscle acetyl-CoA and carnitine moieties

This thesis investigated the impact of sodium acetate infusion on muscle fuel metabolism during low and high intensity exercise and demonstrated a decrease in fat oxidation during the former and a decrease in muscle lactate production during the latter. We propose that the rate of fat oxidation decr...

Full description

Bibliographic Details
Main Author:	Ghasemi, Reza
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Online Access:	https://eprints.nottingham.ac.uk/34588/

Similar Items

Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent
by: Porter, Craig, et al.
Published: (2017)

Skeletal muscle carnitine metabolism during intense exercise in human volunteers
by: Shannon, C.E.
Published: (2016)

Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans
by: Stephens, Francis B., et al.
Published: (2013)

Overexpression of acetyl-CoA carboxylase in Aspergillus terreus to increase lovastatin production
by: Hasan, Hanan, et al.
Published: (2018)

Hexokinase and carnitine palmitoyltransferase activities in flight muscles of grasshopper Valanga nigricornis(burm.)
by: Lee, C. W., et al.
Published: (1983)

Entamoeba histolytica acetyl-CoA synthetase: biomarker of acute amoebic liver abscess
by: Lim, Boon Huat, et al.
Published: (2014)

Protein ingestion acutely inhibits insulin-stimulated muscle carnitine uptake in healthy young men
by: Shannon, Chris E., et al.
Published: (2016)

A multifunctional acetyl-CoA carboxylase gene confers freesing tolerance in arabidopsis thaliana
by: Amid, Azura, et al.
Published: (2009)

Investigation of muscle mass and metabolic regulation in human volunteers: the impact of resistance exercise, pharmacological intervention and obesity
by: Taylor, Tariq Yaqub
Published: (2020)

The role of the pyruvate dehydrogenase complex in the regulation of human skeletal muscle fuel metabolism
by: Laithwaite, David
Published: (2009)

Modulation of muscle protein metabolism through amino acid supplementation and exercise in older women
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)

Mathematical modelling of metabolic pathways in pig muscle
by: Williams, H.E.
Published: (2017)

Amino acids and muscle protein metabolism with aging
by: Satoshi Fujita,
Published: (2009)

Molecular and metabolic regulation of skeletal muscle growth in chicken
by: Olomu, Charles
Published: (2018)

The role of the vitamin D receptor in skeletal muscle protein metabolism
by: Bass, Joseph
Published: (2017)

Reduced muscle oxidative capacity is independent of O2 availability in elderly people
by: Layec, G., et al.
Published: (2013)

The sensitive to freezing3 mutation of Arabidopsis thaliana is a cold-sensitive allele of homomeric acetyl-CoA carboxylase that results in cold-induced cuticle deficiencies
by: Amid, Azura, et al.
Published: (2012)

The impact of Vitamin D on Muscle Metabolism, Bioenergetic Responses and Exercise Performance
by: Romeu Montenegro, Karina
Published: (2021)

The impacts of bed rest and acute trauma on muscle metabolic health in humans
by: Shur, Natalie F.
Published: (2024)

Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24–48 h after exercise in young and old humans
by: Stephens, Francis B., et al.
Published: (2018)

Skeletal muscle modulation and functional recovery after colonic resection
by: Bhalla, Ashish
Published: (2016)

Amino acid modulation of gut hormone release and defining roles of GLP-1 and insulin in muscle microcirculation and metabolism in older age
by: Abdulla, Haitham M.A.
Published: (2018)

Mechanism-based intervention in Non-Alcoholic Fatty Liver Disease: mapping the muscle-liver axis and exploring the effect of L-carnitine on liver fat, insulin sensitivity and mitochondrial energy kinetics
by: Thiagarajan, Prarthana
Published: (2021)

Endotoxin induced muscle wasting in avian and murine skeletal muscle
by: Tarabees, Reda Zakaria Ibrahim
Published: (2011)

Gluteus Medius Muscle Activation During Isometric Muscle Contractions
by: O'Dwyer, C., et al.
Published: (2011)

Obesity appears to be associated with altered muscle protein synthetic and breakdown responses to increased nutrient delivery in older men, but not reduced muscle mass or contractile function.
by: Murton, Andrew J., et al.
Published: (2015)

The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells
by: Crossland, Hannah, et al.
Published: (2018)

Inflammation-mediated muscle metabolic dysregulation local and remote to the site of major abdominal surgery
by: Varadhan, Kristina K., et al.
Published: (2017)

Inflammation-mediated muscle metabolic dysregulation local and remote to the site of major abdominal surgery
by: Varadhan, Krishna K., et al.
Published: (2017)

Glutamine and skeletal muscle
by: Tirapegui, J., et al.
Published: (2015)

The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans
by: Wilkinson, Daniel J., et al.
Published: (2018)

Effectiveness of a community-based muscle strengthening exercise program to increase muscle strength among pre-frail older persons in Malaysia: a pilot study
by: Raja Adnan, Raja Nurzatul Efah, et al.
Published: (2021)

Inhibition of OCTN2-mediated transport of carnitine by etoposide
by: Hu, C., et al.
Published: (2013)

Increased pain from muscle fascia following eccentric exercise : animal and human findings
by: Gibson, William, et al.
Published: (2009)

The effects of a high molecular weight glucose polymer on muscle metabolism and exercise performance in humans
by: Gunner, Frances
Published: (2012)

Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes
by: Murton, Andrew J., et al.
Published: (2016)

Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations
by: Franchi, Martino V., et al.
Published: (2017)

The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome
by: Prior, M., et al.
Published: (2010)

Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression.
by: Mallinson, Joanne E., et al.
Published: (2015)

Development and application of minimally invasive stable isotope tracers’ measures of muscle mass and muscle protein synthesis/breakdown: insights into ageing skeletal muscle
by: Cegielski, Jessica
Published: (2020)