Ion mobility-mass spectrometry reveals conformational flexibility in the deubiquitinating enzyme USP5

Many proteins exhibit conformation flexibility as part of their biological function, whether through the presence of a series of well-defined states or by the existence of intrinsic disorder. Ion mobility spectrometry, in combination with MS (IM–MS), offers a rapid and sensitive means of probing ens...

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Bibliographic Details
Main Authors: Scott, Daniel, Layfield, Robert, Oldham, Neil J.
Format: Article
Published: Wiley 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/34559/