Synthesis of19F nucleic acid–polymer conjugates as real-time MRI probes of biorecognition

Polymer-DNA conjugates in which one nucleic acid strand contains fluorine-substituted nucleobases have been prepared and characterised. The efficacy of these novel 19F nucleic acid − polymer conjugates as sensitive and selective in vitro reporters of DNA binding events is demonstrated through a numb...

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Bibliographic Details
Main Authors: Sicilia, Giovanna, Davis, Adrienne L., Spain, Sebastian G., Magnusson, Johannes P., Boase, Nathan R. B., Thurecht, Kristofer J., Alexander, Cameron
Format: Article
Published: Royal Society of Chemistry 2016
Online Access:https://eprints.nottingham.ac.uk/34466/