Fast global interactive volume segmentation with regional supervoxel descriptors

In this paper we propose a novel approach towards fast multi-class volume segmentation that exploits supervoxels in order to reduce complexity, time and memory requirements. Current methods for biomedical image segmentation typically require either complex mathematical models with slow convergence,...

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Main Authors: Luengo, Imanol, Basham, Mark, French, Andrew P.
Format: Conference or Workshop Item
Published: 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/34250/
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author Luengo, Imanol
Basham, Mark
French, Andrew P.
author_facet Luengo, Imanol
Basham, Mark
French, Andrew P.
author_sort Luengo, Imanol
building Nottingham Research Data Repository
collection Online Access
description In this paper we propose a novel approach towards fast multi-class volume segmentation that exploits supervoxels in order to reduce complexity, time and memory requirements. Current methods for biomedical image segmentation typically require either complex mathematical models with slow convergence, or expensive-to-calculate image features, which makes them non-feasible for large volumes with many objects (tens to hundreds) of different classes, as is typical in modern medical and biological datasets. Recently, graphical models such as Markov Random Fields (MRF) or Conditional Random Fields (CRF) are having a huge impact in different computer vision areas (e.g. image parsing, object detection, object recognition) as they provide global regularization for multiclass problems over an energy minimization framework. These models have yet to find impact in biomedical imaging due to complexities in training and slow inference in 3D images due to the very large number of voxels. Here, we define an interactive segmentation approach over a supervoxel space by first defining novel, robust and fast regional descriptors for supervoxels. Then, a hierarchical segmentation approach is adopted by training Contextual Extremely Random Forests in a user-defined label hierarchy where the classification output of the previous layer is used as additional features to train a new classifier to refine more detailed label information. This hierarchical model yields final class likelihoods for supervoxels which are finally refined by a MRF model for 3D segmentation. Results demonstrate the effectiveness on a challenging cryo-soft X-ray tomography dataset by segmenting cell areas with only a few user scribbles as the input for our algorithm. Further results demonstrate the effectiveness of our method to fully extract different organelles from the cell volume with another few seconds of user interaction. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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format Conference or Workshop Item
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institution University of Nottingham Malaysia Campus
institution_category Local University
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publishDate 2016
recordtype eprints
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spelling nottingham-342502020-05-04T17:40:29Z https://eprints.nottingham.ac.uk/34250/ Fast global interactive volume segmentation with regional supervoxel descriptors Luengo, Imanol Basham, Mark French, Andrew P. In this paper we propose a novel approach towards fast multi-class volume segmentation that exploits supervoxels in order to reduce complexity, time and memory requirements. Current methods for biomedical image segmentation typically require either complex mathematical models with slow convergence, or expensive-to-calculate image features, which makes them non-feasible for large volumes with many objects (tens to hundreds) of different classes, as is typical in modern medical and biological datasets. Recently, graphical models such as Markov Random Fields (MRF) or Conditional Random Fields (CRF) are having a huge impact in different computer vision areas (e.g. image parsing, object detection, object recognition) as they provide global regularization for multiclass problems over an energy minimization framework. These models have yet to find impact in biomedical imaging due to complexities in training and slow inference in 3D images due to the very large number of voxels. Here, we define an interactive segmentation approach over a supervoxel space by first defining novel, robust and fast regional descriptors for supervoxels. Then, a hierarchical segmentation approach is adopted by training Contextual Extremely Random Forests in a user-defined label hierarchy where the classification output of the previous layer is used as additional features to train a new classifier to refine more detailed label information. This hierarchical model yields final class likelihoods for supervoxels which are finally refined by a MRF model for 3D segmentation. Results demonstrate the effectiveness on a challenging cryo-soft X-ray tomography dataset by segmenting cell areas with only a few user scribbles as the input for our algorithm. Further results demonstrate the effectiveness of our method to fully extract different organelles from the cell volume with another few seconds of user interaction. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only. 2016-03-26 Conference or Workshop Item PeerReviewed Luengo, Imanol, Basham, Mark and French, Andrew P. (2016) Fast global interactive volume segmentation with regional supervoxel descriptors. In: SPIE Medical Imaging 2016: Image Processing, 27 February 2016, San Diego, California. Volume Interactive segmentation Random Forest Contextual Information Markov Random Fields http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=2506227 10.1117/12.2216382 10.1117/12.2216382 10.1117/12.2216382
spellingShingle Volume
Interactive segmentation
Random Forest
Contextual Information
Markov Random Fields
Luengo, Imanol
Basham, Mark
French, Andrew P.
Fast global interactive volume segmentation with regional supervoxel descriptors
title Fast global interactive volume segmentation with regional supervoxel descriptors
title_full Fast global interactive volume segmentation with regional supervoxel descriptors
title_fullStr Fast global interactive volume segmentation with regional supervoxel descriptors
title_full_unstemmed Fast global interactive volume segmentation with regional supervoxel descriptors
title_short Fast global interactive volume segmentation with regional supervoxel descriptors
title_sort fast global interactive volume segmentation with regional supervoxel descriptors
topic Volume
Interactive segmentation
Random Forest
Contextual Information
Markov Random Fields
url https://eprints.nottingham.ac.uk/34250/
https://eprints.nottingham.ac.uk/34250/
https://eprints.nottingham.ac.uk/34250/