Time to blip – stochastic simulation of single channel opening

The stochastic dynamics of the inositol-1,4,5-trisphosphate (IP3) receptor (IP3R) is key to understanding a wide range of observed calcium (Ca2+) signals (Falcke 2004). The stochastic nature results from the constant binding and unbinding of Ca2+ and IP3 to and from their respective binding sites an...

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Bibliographic Details
Main Author: Thul, Ruediger
Format: Article
Published: Cold Spring Harbor Laboratory Press 2014
Online Access:https://eprints.nottingham.ac.uk/34108/