Development of an in-vitro epithelial-myofibroblast intestinal model

In vitro studies of drug permeability are traditionally carried out using cultured monolayers of epithelial cell lines grown on semi permeable membranes. Caco-2 cells, which are colon-derived, spontaneously form polarised cell layers when cultured in vitro which are akin to an epithelium of enterocy...

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Bibliographic Details
Main Author: Patient, J.D.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Online Access:https://eprints.nottingham.ac.uk/33617/