Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD

Elastin degradation is a key feature of emphysema and may have a role in the pathogenesis of atherosclerosis associated with chronic obstructive pulmonary disease (COPD). Circulating desmosine is a specific biomarker of elastin degradation. We investigated the association between plasma desmosine (p...

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Bibliographic Details
Main Authors: Rabinovich, Roberto A., Miller, Bruce E., Wrobel, Karolina, Ranjit, Kareshma, Williams, Michelle C., Drost,, Ellen, Edwards, Lisa D., Lomas, David A., Rennard, Stephen I., Agustí, Alvar, Tal-Singer, Ruth, Vestbo, Jørgen, Wouters, Emiel F.M., John, Michelle, van Beek, Edwin J.R., Murchison, John T., Bolton, Charlotte E., MacNee, William, Huang, Jeffrey T.J.
Format: Article
Published: European Respiratory Society 2016
Online Access:https://eprints.nottingham.ac.uk/33390/