A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain
Factor XI (FXI) is the zymogen of FXIa, which cleaves FIX in the intrinsic pathway of coagulation. FXI is known to exist as a dimer and interacts with multiple proteins via its 4 apple domains in the “saucer section” of the enzyme; however, to date, no complex crystal structure has been described. T...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
American Society of Hematology
2016
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| Online Access: | https://eprints.nottingham.ac.uk/33370/ |