Impaired burrowing is the most prominent behavioral deficit of aging htau mice

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Impaired burrowing is the most prominent behavioral deficit of aging htau mice

htau mice are deficient of murine tau but express all six human tau isoforms, leading to gradual tau misprocessing and aggregation in brain areas relevant to Alzheimer's disease. Whilst histopathological changes in htau mice have been researched in the past, we focused here on functional conseq...

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Bibliographic Details
Main Authors:	Geiszler, Philippine C., Barron, Matthew, Pardon, Marie-Christine
Format:	Article
Published:	Elsevier 2016
Subjects:	Htau; Tau knock-out; Cognition; Behaviour; Tauopathy Alzheimer's disease
Online Access:	https://eprints.nottingham.ac.uk/33360/

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