Bacterial crowd control: AIP-based analogues and solonamides modulate staphylococcal virulence

This thesis details research in three areas, in attempts to produce more effective inhibitors of the staphylococcal agr quorum sensing system. The non-ribosomal peptide synthase biosynthetic cluster responsible for the production of the aureusimines represents roughly 0.5% of the S. aureus genome. H...

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Bibliographic Details
Main Author: Hampson, Robert W.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/33344/