A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress

Pro- and eukaryotes produce melanin for protection from environmental stress or as virulence determinant. The human pathogenic fungus Aspergillus fumigatus and related Ascomycetes produce dihydroxynaphthalene (DHN) melanin in conidia, which is essential for inhibiting phagolysosome acidification. In...

Full description

Bibliographic Details
Main Authors: Geib, Elena, Gressler, Markus, Viediernikova, Iuliia, Hillmann, Falk, Jacobsen, Ilse D., Nietzsche, Sandor, Hertweck, Christian, Brock, Matthias
Format: Article
Published: Elsevier 2016
Online Access:https://eprints.nottingham.ac.uk/33069/