Studies on the cell autonomous role for notch in definitive haematopoiesis and Tet genes' requirements in early organogenesis
In vertebrates, haematopoiesis is maintained by self-renewing multipotent haematopoietic stem cells (HSCs) in the adult bone marrow. HSCs are specified and generated during early embryonic development from arterial endothelial cells in the ventral wall of the dorsal aorta (vDA) that become haemogenic...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2016
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| Online Access: | https://eprints.nottingham.ac.uk/32971/ |