NMNAT1 and its role on ageing and age-realted diseases

NAD metabolism is increasingly implicated in a variety of biological functions, including regulation of gene transcription, lifespan, cell death, circadian rhythm and glucose home-ostasis. The three mammalian isoforms of the central NAD biosynthetic enzyme, nicotin-amide mononucleotide adenylyltrans...

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Bibliographic Details
Main Author: Rossi, Francesca
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Online Access:https://eprints.nottingham.ac.uk/32932/