Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma
Infantile haemangioma (IH), the most common neoplasm in infants, is a slowly resolving vascular tumour. Vascular endothelial growth factor A (VEGF-A), which consists of both the pro- and anti-angiogenic variants, contributes to the pathogenesis of IH. However, the roles of different VEGF-A variants...
| Main Authors: | Ye, Xi, Abou-Rayyah, Yassir, Bischoff, Joyce, Ritchie, Alison, Sebire, Neil J., Watts, Patrick, Churchill, Amanda J., Bates, David O. |
|---|---|
| Format: | Article |
| Published: |
Wiley Blackwell
2016
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/32863/ |
Similar Items
Effects of omentin on endothelial disruption and hydrogen peroxide-induced inflammation in vascular endothelial cell monolayer
by: Kamaruddin, Nur Aqilah
Published: (2022)
by: Kamaruddin, Nur Aqilah
Published: (2022)
VEGF-A165b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney
by: Stevens, Megan, et al.
Published: (2017)
by: Stevens, Megan, et al.
Published: (2017)
Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2
by: Peach, Chloe, et al.
Published: (2018)
by: Peach, Chloe, et al.
Published: (2018)
Pre-eclampsia: the role of vascular endothelial growth factor and its interaction with the vascular endothelium
by: Brockelsby, Jeremy Charles
Published: (2001)
by: Brockelsby, Jeremy Charles
Published: (2001)
Control of collateral formation as a therapeutic for cardiovascular disease
by: Amartey, Jason
Published: (2024)
by: Amartey, Jason
Published: (2024)
Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)
by: Barratt, Shaney L., et al.
Published: (2018)
by: Barratt, Shaney L., et al.
Published: (2018)
Identification of genes and pathways regulated by the PRH/HHEX transcription factor in endothelial and lymphatic cells
by: Dahhan, Rania
Published: (2024)
by: Dahhan, Rania
Published: (2024)
Mechanisms of interferon-gamma (IFN-y)-induced hyperpermeability changes in human umbilical vein endothelial cells
by: Ng, Chin Theng
Published: (2017)
by: Ng, Chin Theng
Published: (2017)
Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain
by: Ved, Nikita, et al.
Published: (2018)
by: Ved, Nikita, et al.
Published: (2018)
The effect of quorum sensing molecules on vascular function
by: Alassaf, Fawaz A.
Published: (2018)
by: Alassaf, Fawaz A.
Published: (2018)
In vitro anti-atherogenic effects of asiatic acid in human aortic endothelial cells
by: Fong, Lai Yen
Published: (2016)
by: Fong, Lai Yen
Published: (2016)
Dynamics of cytokine induced E-selectin expression in endothelial cells
by: Ogrodzinski, Lydia
Published: (2023)
by: Ogrodzinski, Lydia
Published: (2023)
Properties of asiaticoside in suppressing hyperpermeability in human umbilical vein endothelial cells induced by interferon-gamma
by: Khairudin, Nurnabila Huda
Published: (2016)
by: Khairudin, Nurnabila Huda
Published: (2016)
Identification of long non-coding RNAs in serum exosomes from colorectal cancer patients and effects of exosomes on tube formation by endothelial cells
by: Ng, Chin Tat
Published: (2019)
by: Ng, Chin Tat
Published: (2019)
The cardiovascular and functional consequences of arteriovenous fistula formation in chronic kidney disease
by: Korsheed, Shvan
Published: (2011)
by: Korsheed, Shvan
Published: (2011)
Peripheral contributions to the development and maintenance of inflammation and pain in arthritis
by: Amanitis, Dimitrios
Published: (2022)
by: Amanitis, Dimitrios
Published: (2022)
Cellular and molecular mechanisms underlying extravasation of human Wharton’s jelly mesenchymal stem cells across fetal and adult endothelial cell monolayers
by: Ebrahim, Neven
Published: (2016)
by: Ebrahim, Neven
Published: (2016)
The relationship between in-vitro endothelial permeability and molecules of the intercellular junction
by: Budworth, Rachel Ann
Published: (2003)
by: Budworth, Rachel Ann
Published: (2003)
In vitro protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on junctional protein disruption and the underlying signaling pathways in lipopolysaccharide-induced endothelial hyperpermeability
by: Chan, Yee Han
Published: (2022)
by: Chan, Yee Han
Published: (2022)
The effect of gestational diabetes on human umbilical mesenchymal stem cells and their ability to influence endothelial permeability
by: Salem, Samar
Published: (2023)
by: Salem, Samar
Published: (2023)
Expression profiling of genes related to endothelial cell function in pre-diabetes and type 2 diabetes subjects
by: Moradipoor, Sara
Published: (2016)
by: Moradipoor, Sara
Published: (2016)
Dynamics of VEGF-A binding at VEGFR2 and NRP1
by: Peach, Chloe J
Published: (2020)
by: Peach, Chloe J
Published: (2020)
The cardiovascular profile and pharmacology of vandetanib and pazopanib
by: Carter, Joanne
Published: (2017)
by: Carter, Joanne
Published: (2017)
Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and desmitis: case reports
by: Kovac, Milomir, et al.
Published: (2017)
by: Kovac, Milomir, et al.
Published: (2017)
Differential regulation of blood flow induced neovascularisation and mural cell recruitment by VEGF and angiopoietin signaling
by: Stone, Oliver A., et al.
Published: (2017)
by: Stone, Oliver A., et al.
Published: (2017)
Exploring the potential role of endothelial ZEB1 in developmental and pathological angiogenesis
by: Green, Kathryn
Published: (2025)
by: Green, Kathryn
Published: (2025)
Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development
by: Metzler, Veronika M., et al.
Published: (2017)
by: Metzler, Veronika M., et al.
Published: (2017)
Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response
by: Smith, Stuart J., et al.
Published: (2015)
by: Smith, Stuart J., et al.
Published: (2015)
Elucidating the role of hyperglycaemia in endothelial cell and pericyte morphology, function and crosstalk, and blood-brain barrier integrity
by: Hashmat, Arshad
Published: (2024)
by: Hashmat, Arshad
Published: (2024)
Blood-Brain Barrier on-a-chip model for the study of drug permeability into the brain
by: Whitehouse, Chloe Ann
Published: (2022)
by: Whitehouse, Chloe Ann
Published: (2022)
The Effect of Carbon Disulfide on Oxidative Injury in Vein Endothelial Cells
by: Chen, S., et al.
Published: (2006)
by: Chen, S., et al.
Published: (2006)
Negative correlation between Placental Growth Factor and Endocan-1 in women with preeclampsia
by: Ribiero Hentchke, Marta, et al.
Published: (2018)
by: Ribiero Hentchke, Marta, et al.
Published: (2018)
Effects of small molecule inhibitors targeting PI3K, EGFR, IGF-1R, MTOR, SMAD3 and MEK in tube formation and 3-D spheroid assay
by: Ng, Chin Tat
Published: (2014)
by: Ng, Chin Tat
Published: (2014)
The role of outgrowth endothelial cells as therapeutics for ischaemic injury-mediated cerebrovascular damage: impact of NOX2 inhibitor
by: Alwjwaj, Mansour
Published: (2022)
by: Alwjwaj, Mansour
Published: (2022)
Attenuation of chronic tension headache frequency and severity with daily l-arginine and aged garlic extract dietary supplementation
by: Chaliha, Devahuti, et al.
Published: (2021)
by: Chaliha, Devahuti, et al.
Published: (2021)
Expression profiling of genes related to endothelial cells biology in patients with type 2 diabetes and patients with pre-diabetes
by: Moradipoor, Sara, et al.
Published: (2016)
by: Moradipoor, Sara, et al.
Published: (2016)
Myocardial infarction after intravitreal vascular endothelial growth factor inhibitors: a whole population study
by: Kemp, A., et al.
Published: (2013)
by: Kemp, A., et al.
Published: (2013)
A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis
by: Thambyrajah, Roshana Sutharshini, et al.
Published: (2016)
by: Thambyrajah, Roshana Sutharshini, et al.
Published: (2016)
A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis.
by: Thambyrajah, Roshana Sutharshini, et al.
Published: (2016)
by: Thambyrajah, Roshana Sutharshini, et al.
Published: (2016)
Osteocalcin and the vasculature
by: Millar, Sophie
Published: (2020)
by: Millar, Sophie
Published: (2020)
Similar Items
-
Effects of omentin on endothelial disruption and hydrogen peroxide-induced inflammation in vascular endothelial cell monolayer
by: Kamaruddin, Nur Aqilah
Published: (2022) -
VEGF-A165b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney
by: Stevens, Megan, et al.
Published: (2017) -
Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2
by: Peach, Chloe, et al.
Published: (2018) -
Pre-eclampsia: the role of vascular endothelial growth factor and its interaction with the vascular endothelium
by: Brockelsby, Jeremy Charles
Published: (2001) -
Control of collateral formation as a therapeutic for cardiovascular disease
by: Amartey, Jason
Published: (2024)