Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma

Infantile haemangioma (IH), the most common neoplasm in infants, is a slowly resolving vascular tumour. Vascular endothelial growth factor A (VEGF-A), which consists of both the pro- and anti-angiogenic variants, contributes to the pathogenesis of IH. However, the roles of different VEGF-A variants...

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Bibliographic Details
Main Authors: Ye, Xi, Abou-Rayyah, Yassir, Bischoff, Joyce, Ritchie, Alison, Sebire, Neil J., Watts, Patrick, Churchill, Amanda J., Bates, David O.
Format: Article
Published: Wiley Blackwell 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/32863/