Secretory leukocyte protease inhibitor gene deletion
alters bleomycin-induced lung injury, but not
development of pulmonary fibrosis

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Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

Idiopathic pulmonary fibrosis is a progressive, fatal disease with limited treatment options. Protease-mediated transforming growth factor-β (TGF-β) activation has been proposed as a pathogenic mechanism of lung fibrosis. Protease activity in the lung is tightly regulated by protease inhibitors, par...

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Bibliographic Details
Main Authors:	Habgood, Antony, Tatler, Amanda L., Porte, Joanne, Wahl, Sharon, M., Laurent, Geoffrey, J., John, Alison, E., Johnson, Simon, R., Jenkins, Gisli
Format:	Article
Published:	Nature Publishing Group 2016
Online Access:	https://eprints.nottingham.ac.uk/32862/

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