Vascular change and opposing effects of the angiotensin type 2 receptor in a mouse model of vascular cognitive impairment

Vascular change and opposing effects of the angiotensin type 2 receptor in a mouse model of vascular cognitive impairment

Our aims were to assess the spatiotemporal development of brain pathology in a mouse model of chronic hypoperfusion using magnetic resonance imaging (MRI), and to test whether the renin-angiotensin system (RAS) can offer therapeutic benefit. For the first time, different patterns of cerebral blood f...

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Bibliographic Details
Main Authors: Füchtemeier, Martina, Brinckmann, Marie P., Foddis, Marco, Kunz, Alexander, Po, Chrystelle, Curato, Caterina, Dirnagl, Ulrich, Farr, Tracy D.
Format: Article
Published: Nature Publishing Group 2015
Subjects:
Angiotensin II receptor type 2; Diffusion tensor imaging; Mouse hypoperfusion; Perfusion weighted imaging; Vascular cognitive impairment
Online Access:https://eprints.nottingham.ac.uk/32792/

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https://eprints.nottingham.ac.uk/32792/

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