Design, synthesis and evaluation of MRI ligands for in vivo imaging of protease activity
This thesis details the design and synthesis of a small library of 19F MRI MMP probes containing an MMP substrate bound to a paramagnetic agent (gadolinium contrast agent) with a fluorine containing group at the opposite terminus. The largest obstacle in the synthesis of the probe was the conjugatio...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2016
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| Online Access: | https://eprints.nottingham.ac.uk/32777/ |