Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma
Airway remodelling describes the histopathological changes leading to fixed airway obstruction in patients with asthma and includes extra-cellular matrix (ECM) deposition. Matrix metalloproteinase-1 (MMP-1) is present in remodelled airways but its relationship with ECM proteins and the resulting fun...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Public Library of Science
2014
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| Online Access: | https://eprints.nottingham.ac.uk/32644/ |