Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin

Unanchored polyubiquitin chains are emerging as importanregulators of cellular physiology with diverse roles paralleling those of substrate-conjugated polyubiquitin. However tools able to discriminate unanchored polyubiquitin chains of different isopeptide linkages have not been described. We descri...

Full description

Bibliographic Details
Main Authors: Scott, Daniel, Garner, Tom P., Long, Jed, Strachan, Jo, Mistry, Sharad C., Bottrill, Andrew R., Tooth, David J., Searle, Mark S., Oldham, Neil J., Layfield, Rob
Format: Article
Published: Wiley-VCH Verlag 2016
Online Access:https://eprints.nottingham.ac.uk/32622/