Cardiac responses to hypoxia: the role of pyruvate dehydrogenase complex in carbohydrate utilisation

Accelerated carbohydrate utilisation and suppressed lipid oxidative metabolism are hallmarks of heart failure (HF). Hypoxia mimics failing heart metabolic reprogramming and has been suggested to play a role in cardiac metabolic switch. One aspect of the regulation of cardiac energy metabolism is the...

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Bibliographic Details
Main Author: Handzlik, Michal
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Online Access:https://eprints.nottingham.ac.uk/32119/