The limitations of in vitro experimentation in understanding biofilms and chronic infection

QR Code

The limitations of in vitro experimentation in understanding biofilms and chronic infection

We have become increasingly aware that during infection, pathogenic bacteria often grow in multi- cellular biofilms which are often highly resistant to antibacterial strategies. In order to understand how biofilms form and contribute to infection, in vitro biofilm systems such as microtitre plate as...

Full description

Bibliographic Details
Main Authors:	Roberts, Aled, Kragh, Kasper, Bjarnsholt, Thomas, Diggle, Stephen P.
Format:	Article
Published:	Elsevier 2015
Subjects:	biofilm; chronic infection
Online Access:	https://eprints.nottingham.ac.uk/31950/

Similar Items

An ex vivo lung model to study bronchioles infected with Pseudomonas aeruginosa biofilms
by: Harrison, Freya, et al.
Published: (2016)

Action of linezolid or vancomycin on biofilms in ventriculoperitoneal shunts in vitro
by: Bayston, Roger, et al.
Published: (2012)

Biofilm formation of multidrug-resistant Staphylococcus aureus on stainless steel surfaces and the effect of disinfectants in eliminating biofilm
by: Jamaludin, Nur Syifa'
Published: (2019)

Cousins, siblings, or copies: the genomics of recurrent Staphylococcus aureus infections in chronic rhinosinusitis
by: Drilling, A., et al.
Published: (2014)

Exploring the structure, regulation, and function of the surface tethered Pseudomonas aeruginosa virulence factor, AaaA, and its role in maintaining chronic wound infections
by: Laxton, Claire. S.
Published: (2023)

Lectin-mediated biofilm maturation, quorum sensing and Pseudomonas aeruginosa infections in cystic fibrosis
by: Crusz, S.A.
Published: (2009)

In vitro study of effects of antibiotics on Pseudomonas aeruginosa biofilm formation
by: Jeevajothi Nathan, Priadarssini
Published: (2017)

Gentamicin-Coated Hydroxyapatite in Prevention of Biofilm Formation in Bone Tissue
by: Au, Lee Fong
Published: (2011)

Understanding the diversity and evolution of complex wound infections
by: da Silva, Ana C.
Published: (2019)

Poor functional antibody responses are present in nearly all patients with chronic lymphocytic leukaemia, irrespective of total IgG concentration, and are associated with increased risk of infection
by: Parry, Helen Marie, et al.
Published: (2015)

INFLUENCE OF POLYMER SURFACES ON BACTERIAL BIOFILM FORMATION
by: Sanni, Olutoba
Published: (2020)

Chemical oxygen demand removal using artificially constructed biofilm by dielectrophoresis on wirecloth electrode
by: Wai, York Chow
Published: (2014)

Role of multicellular aggregates in biofilm formation
by: Kragh, Kasper, et al.
Published: (2016)

Characterization of biofilm formation in Bacillus subtilis isolated from radiation and non radiation-emitting hot springs
by: Ali, Dhuha Saeed
Published: (2019)

Phosphate based glass thin films for biofilm prevention in orthopaedic implants
by: Thomas, Kathryn G.
Published: (2020)

Bacterial biofilm interactions with human immune cells
by: Lee, Kelly
Published: (2023)

Role of lectin receptors in recognition of Pseudomonas aeruginosa biofilms
by: Almuhanna, Yasir Saleh I
Published: (2021)

Effect of biofilms grown at various chloramine residuals on chloramine decay
by: Adhikari, Rekha, et al.
Published: (2012)

Development and validation of a biofilm model to establish the effect of chemical and physical treatments on cellular viability
by: Wells, Victoria
Published: (2023)

Characterization and growth optimization of marine fungi, and antibacterial and biofilm removal activities of its extracts
by: Mat Daud, Noor Ifatul Hanim
Published: (2016)

Evaluation of granular-activated carbon-attached biofilm coated in alginate-chitosan for biohydrogen production
by: Dzul Rashidi, Nur Farahana
Published: (2022)

Atmospheric air plasma induces increased cell aggregation during the formation of Escherichia coli biofilms
by: Kwandou, Goldina, et al.
Published: (2018)

Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
by: Hurley, M.N., et al.
Published: (2012)

Understanding the relationship between chronic pain and emotional disorders
by: Tadjibaev, Arman
Published: (2021)

Effect of detergent, herbs and spices on the growth of Vibrio parahaemolyticus biofilm in seafood
by: Nillian, Elexson
Published: (2014)

Antibiotic resistance and biofilm-forming properties of bacteria from horses’ wound
by: Ahmad Nadzir, Nur Adilah
Published: (2017)

Investigating microbial biofilms within washing machines: novel nanosensor technology enables insights into pH gradients of Pseudomonas aeruginosa biofilms
by: Hollmann, Birte
Published: (2021)

Microwave synthesis of novel methacrylate monomers designed to reduce biofilm formation to surfaces
by: Dundas, Adam Alastair
Published: (2018)

The structural functionalisation of poly(ß-amino esters) for drug delivery to bacterial biofilms
by: Kasza, Karolina Anna
Published: (2024)

Identification and characterization of biofilm-producing clinical isolates of staphylococcus aureus
by: Atshan, Salman Sahab
Published: (2013)

What are the main drivers for public policies to prevent healthcare-associated infections?
by: Padoveze, Maria Clara, et al.
Published: (2018)

Otitis media with effusion: current treatment, new understanding of its aetiopathogenesis, and a novel therapeutic approach
by: Daniel, Matija
Published: (2013)

The formation of malodorous dimethyl oligosulphides in treated groundwater: the role of biofilms and potential precursors.
by: Franzmann, Peter, et al.
Published: (2001)

Reduction of antimicrobial resistance through antimicrobial stewardship
by: Saxby, Claire F.
Published: (2020)

Epidemiology of Leptospirainterrogans Serovar Hardjo Infection in Cattle
by: Bejo, Siti Khairani
Published: (2001)

TYPLEX® Chelate, a novel feed additive, inhibits Campylobacter jejuni biofilm formation and cecal colonization in broiler chickens
by: Khattak, Farina, et al.
Published: (2018)

Gene expression patterns induced by human rhinovirus species B infection using an In Vitro model of human type II alveolar pulmonary epithelial cell line
by: Etemadi, Mohammadreza
Published: (2016)

In vitro and in vivo effects of palm kernel cake oligosaccharides on Salmonella enterica serovar enteritidis infection
by: Foo, Rui Qing
Published: (2021)

Effects of green silver nanoparticles on bacterial-infected in vitro Eucalyptus pellita F.Muell plant
by: Sawalha, Hanadi Akram Naser
Published: (2023)

Assessing the influence of fibre type and biofilms on the ingestion and retention of microfibres by freshwater invertebrates
by: Evans, Isobel
Published: (2025)