The limitations of in vitro experimentation in understanding biofilms and chronic infection

We have become increasingly aware that during infection, pathogenic bacteria often grow in multi- cellular biofilms which are often highly resistant to antibacterial strategies. In order to understand how biofilms form and contribute to infection, in vitro biofilm systems such as microtitre plate as...

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Bibliographic Details
Main Authors: Roberts, Aled, Kragh, Kasper, Bjarnsholt, Thomas, Diggle, Stephen P.
Format: Article
Published: Elsevier 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/31950/