Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response
Aims: Recent studies have observed that cells from high-grade glial tumors are capable of assuming an endothelial phenotype and genotype, a process termed ‘vasculogenic mimicry’ (VM). Here we model and manipulate VM in dynamic 3-dimensional (3D) glioma cultures. Methods: The Rotary Cell Culture Syst...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Impact Journals
2015
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/31768/ |