Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels

Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels

The soluble cleaved urokinase plasminogen activator receptor (scuPAR) is a circulating protein detected in multiple diseases, including various cancers, cardiovascular disease, and kidney disease, where elevated levels of scuPAR have been associated with worsening prognosis and increased disease agg...

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Bibliographic Details
Main Authors: Portelli, Michael, Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H., Sayers, Ian
Format: Article
Published: Federation of American Society of Experimental Biology 2014
Subjects:
GWAS
Proteolysis
Respiratory disease
HBECs
Cellular proliferation and wound repair
Online Access:https://eprints.nottingham.ac.uk/3171/

Internet

https://eprints.nottingham.ac.uk/3171/

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