A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis
Selective silencing of the cyclooxygenase-2 (COX-2) gene with the loss of the antifibrotic mediator PGE2 contributes to the fibrotic process in idiopathic pulmonary fibrosis (IPF). This study explored the role of G9a- and EZH2-mediated methylation of histone H3 lysine 9 (H3K9me3) and 27 (H3K27me3) i...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Federation of American Society of Experimental Biology
2014
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| Online Access: | https://eprints.nottingham.ac.uk/31459/ |