Total loss of MHC class I is an independent indicator of good prognosis in breast cancer

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Total loss of MHC class I is an independent indicator of good prognosis in breast cancer

Tumours can be recognised by CTL and NK cells. CTL recognition depends on expression of MHC Class I loaded with peptides from tumour antigens. In contrast, loss of MHC Class I results in NK activation. In our study a large set of samples from patients with primary operable invasive breast cancer was...

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Bibliographic Details
Main Authors:	Madjd, Zahra, Spendlove, Ian, Pinder, Sarah E., Ellis, Ian O., Durrant, Lindy G.
Format:	Article
Published:	Wiley 2005
Subjects:	Breast tissue microarray HC10 Prognostic factor MHC Class I Immunohistochemistry
Online Access:	https://eprints.nottingham.ac.uk/3145/

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