Total loss of MHC class I is an independent indicator of good prognosis in breast cancer
Tumours can be recognised by CTL and NK cells. CTL recognition depends on expression of MHC Class I loaded with peptides from tumour antigens. In contrast, loss of MHC Class I results in NK activation. In our study a large set of samples from patients with primary operable invasive breast cancer was...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Wiley
2005
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/3145/ |