Identification of Escherichia coli ygaQ and rpmG as novel mitomycin C resistance factors implicated in DNA repair

Using the ASKA (A Complete Set of E. coli K-12 ORF Archive) library for genome-wide screening of E. coli proteins we identified that expression of ygaQ and rpmG promotemitomycin C resistance (MMCR). YgaQ mediated MMCR was independent of homologous recombination involving RecA or RuvABC, but re...

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Bibliographic Details
Main Authors: Bolt, Edward L., Jenkins, Tabitha, Russo, Valeria Moreira, Ahmed, Sharlene, Cavey, James, Cass, Simon
Format: Article
Published: Portland Press: 2015
Online Access:https://eprints.nottingham.ac.uk/31311/