DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS

DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS

Aims: Alterations in DNA methylation contribute to the abnormal phenotype of fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA). Herein, we performed genome-wide DNA methylation profiling of RA FLS derived from synovial fluid, a more readily accessible source of disease-...

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Bibliographic Details
Main Authors: Glossop, John R., Haworth, Kim E., Emes, Richard D., Nixon, Nicola B., Packham, Jon C., Dawes, Peter T., Fryer, Anthony A., Mattey, Derek L., Farrell, William E.
Format: Article
Published: Future Medicine 2015
Subjects:
Rheumatoid arthritis; DNA Methylation; Fibroblast-like synoviocyte; Synovial fluid; Epigenetics; Osteoarthritis
Online Access:https://eprints.nottingham.ac.uk/31130/

Internet

https://eprints.nottingham.ac.uk/31130/

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