A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea

Background: Irritable bowel syndrome with diarrhoea (IBS-D) is particularly debilitating due to urgency and episodic incontinence. Some 5-hydroxytryptamine 3 (5-HT3) receptor antagonists (5-HT3RAs) have proven effective but have serious side effects. Ondansetron, also a 5-HT3RA, has been widely used...

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Bibliographic Details
Main Authors: Garsed, Klara, Chernova, Julia, Hastings, Margaret, Lam, Ching, Marciani, Luca, Singh, Gulzar, Henry, Amanda P., Hall, Ian P., Whorwell, Peter, Spiller, Robin C.
Format: Article
Published: BMJ Publishing Group 2013
Online Access:https://eprints.nottingham.ac.uk/3087/