Identifying the protein interactions of Mre11-Rad50 in Haloferax volcanii during double-strand break repair

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Identifying the protein interactions of Mre11-Rad50 in Haloferax volcanii during double-strand break repair

The Mre11 and Rad50 proteins are found in all domains of life and form a complex that locates and binds to DNA double-strand breaks (DSBs). The complex tethers DNA ends and coordinates the repair of DSBs. In Haloferax volcanii, mre11rad50 mutants are more resistant to DNA damage than the wild-type....

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Bibliographic Details
Main Author:	Wickham-Smith, Charlie
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2015
Online Access:	https://eprints.nottingham.ac.uk/30816/

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