Identifying the protein interactions of Mre11-Rad50 in Haloferax volcanii during double-strand break repair
The Mre11 and Rad50 proteins are found in all domains of life and form a complex that locates and binds to DNA double-strand breaks (DSBs). The complex tethers DNA ends and coordinates the repair of DSBs. In Haloferax volcanii, mre11rad50 mutants are more resistant to DNA damage than the wild-type....
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2015
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| Online Access: | https://eprints.nottingham.ac.uk/30816/ |