Conversion of a non-selective adenosine receptor antagonist into A3-selective high affinity fluorescent probes using peptide-based linkers

Advances in fluorescence-based imaging technologies have helped propel the study of real-time biological readouts and analysis across many different areas. In particular the use of fluorescent ligands as chemical tools to study proteins such as G protein-coupled receptors (GPCRs) has received ongoin...

Full description

Bibliographic Details
Main Authors: Vernall, Andrea J., Stoddart, Leigh A., Briddon, Stephen J., Ng, Hui Wen, Laughton, Charles A., Doughty, Stephen W., Hill, Stephen J., Kellam, Barrie
Format: Article
Published: Royal Society of Chemistry 2013
Online Access:https://eprints.nottingham.ac.uk/3035/