Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics
Background and Purpose Clinical use of cinacalcet in hyperparathyroidism is complicated by its tendency to induce hypocalcaemia, arising partly from activation of calcium-sensing receptors (CaS receptors) in the thyroid and stimulation of calcitonin release. CaS receptor allosteric modulators that...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Published: |
Wiley
2014
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| Online Access: | https://eprints.nottingham.ac.uk/30313/ |