Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome
Background: Phage-encoded serine integrases, such as φC31 integrase, are widely used for genome engineering. Fifteen such integrases have been described but their utility for genome engineering has not been compared in uniform assays. Results: We have compared fifteen serine integrases for their u...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
BioMec Central
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2976/ |