Molecular ageing of alpha- and beta-synucleins: protein damage and repair mechanisms

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Molecular ageing of alpha- and beta-synucleins: protein damage and repair mechanisms

Abnormal α-synuclein aggregates are hallmarks of a number of neurodegenerative diseases. Alpha synuclein and β-synucleins are susceptible to post-translational modification as isoaspartate protein damage, which is regulated in vivo by the action of the repair enzyme protein L-isoaspartyl O-methyltra...

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Bibliographic Details
Main Authors:	Vigneswara, Vasanthy, Cass, Simon, Wayne, Declan, Bolt, Edward L., Ray, David E., Carter, Wayne
Format:	Article
Published:	Public Library of Science 2013
Online Access:	https://eprints.nottingham.ac.uk/2971/

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