Multiscale modelling of drug-polymer nanoparticle assembly identifies parameters influencing drug encapsulation efficiency
Using a multiscale (dual resolution) approach combining an atomistic (GROMOS96) and coarse-grain (MARTINI) force field, we have been able to simulate the process of drug-polymer nanoparticle assembly by nanoprecipitation from mixed solvents. Here we present the development and application of this me...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2015
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/29664/ |