Discovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action

Discovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action

A series of dibasic des-hydroxy β2 receptor agonists has been prepared and evaluated for potential as inhaled ultra-long acting bronchodilators. Determination of activities at the human β-adrenoreceptors demonstrated a series of highly potent and selective β2 receptor agonists that were progressed...

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Bibliographic Details
Main Authors: Stocks, Michael, Alcaraz, Lilian, Bailey, Andrew, Bonnert, Roger, Cadogan, Elaine, Christie, Jadeen, Dixon, John, Connolly, Stephen, Cook, Anthony, Fisher, Adrian, Flaherty, Alice, Humphries, Alexander, Ingall, Anthony, Jordan, Stephen, Lawson, Mandy, Mullen, Alex, Nicholls, David, Paine, Stuart, Pairaudeau, Garry, Young, Alan
Format: Article
Published: American Chemical Society 2014
Online Access:https://eprints.nottingham.ac.uk/2950/

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https://eprints.nottingham.ac.uk/2950/

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