STAT1 signaling is not regulated by a phosphorylation-acetylation switch

The treatment of cells with histone deacetylase inhibitors (HDACi) was reported to reveal the acetylation of STAT1 at lysine 410 and lysine 413 (O. H. Kra¨mer et al., Genes Dev. 20:473–485, 2006). STAT1 acetylation was proposed to regulate apoptosis by facilitating binding to NF-B and to control i...

Full description

Bibliographic Details
Main Authors: Antunes, Filipa, Marg, Andreas, Vinkemeier, Uwe
Format: Article
Published: American Society for Microbiology 2011
Online Access:https://eprints.nottingham.ac.uk/2936/