Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs

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Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs

MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA are located within introns of protein coding gene...

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Bibliographic Details
Main Authors:	Dhir, Ashish, Dhir, Somdutta, Proudfoot, Nick J., Jopling, Catherine L.
Format:	Article
Published:	Nature Publishing Group 2015
Subjects:	miRNA lncRNA transcription termination gene expression
Online Access:	https://eprints.nottingham.ac.uk/29221/

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