Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs
MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA are located within introns of protein coding gene...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2015
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/29221/ |