High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance

Respiratory epithelial cells play a key role in influenza A virus (IAV) pathogenesis and host innate response. Transformed human respiratory cell lines are widely used in the study of IAV−host interactions due to their relative convenience, and inherent difficulties in working with primary cells. Tr...

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Bibliographic Details
Main Authors: Seng, Lai-Giea, Daly, Janet M., Chang, Kin-Chow, Kuchipudi, Suresh V.
Format: Article
Published: Public Library of Science 2014
Online Access:https://eprints.nottingham.ac.uk/29214/