Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function

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Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function

Swap70 functions as a guanine nucleotide exchange factor for Rac and RhoA regulating F-actin cytoskeletal rearrangements and playing a crucial role in mammalian cell activation, migration, adhesion and invasion. Here we show that the zebrafish orthologue, Swap70b, is required for convergent and exte...

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Bibliographic Details
Main Authors:	Xu, Xiaoou, Shuen, Wai Ho, Chen, Chen, Goudevenou, Katerina, Jones, Peter, Sablitzky, Fred
Format:	Article
Published:	Elsevier 2014
Subjects:	Swap70; Guanine nucleotide exchange factor; Convergent and extension cell movement; Gastrulation; Wnt11; Non-canonical Wnt signalling pathway; Def6
Online Access:	https://eprints.nottingham.ac.uk/2917/

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