Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function

Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function

Swap70 functions as a guanine nucleotide exchange factor for Rac and RhoA regulating F-actin cytoskeletal rearrangements and playing a crucial role in mammalian cell activation, migration, adhesion and invasion. Here we show that the zebrafish orthologue, Swap70b, is required for convergent and exte...

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Bibliographic Details
Main Authors: Xu, Xiaoou, Shuen, Wai Ho, Chen, Chen, Goudevenou, Katerina, Jones, Peter, Sablitzky, Fred
Format: Article
Published: Elsevier 2014
Subjects:
Swap70; Guanine nucleotide exchange factor; Convergent and extension cell movement; Gastrulation; Wnt11; Non-canonical Wnt signalling pathway; Def6
Online Access:https://eprints.nottingham.ac.uk/2917/

Internet

https://eprints.nottingham.ac.uk/2917/

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