An investigation into IgE-facilitated allergen recognition and presentation by human dendritic cells

Background: Allergen recognition by dendritic cells (DCs) is a key event in the allergic cascade leading to production of IgE antibodies. C-type lectins, such as the mannose receptor and DC-SIGN, were recently shown to play an important role in the uptake of the house dust mite glycoallergen Der p 1...

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Main Authors: Sharquie, Inas K., Al-Ghouleh, Abeer, Fitton, Patricia, Clark, Mike R., Armour, Kathryn L., Sewell, Herb F., Shakib, Farouk, Ghaemmaghami, Amir M.
Format: Article
Published: BioMed Central 2013
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Online Access:https://eprints.nottingham.ac.uk/2907/