Protective role of female gender in programmed accelerated renal aging in the rat

The aging kidney exhibits a progressive decline in glomerular filtration rate, accompanied by inflammatory and oxidative damage. We hypothesized that accelerated, age-related progression of renal injury is ovarian hormones-dependant. To address this we used an established model of developmentally prog...

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Bibliographic Details
Main Authors: Pijacka, Wioletta, Clifford, Bethan, Tilburgs, Chantal, Joles, Jaap A., Langley-Evans, Simon C., McMullen, Sarah
Format: Article
Published: Wiley Open Access 2015
Online Access:https://eprints.nottingham.ac.uk/28727/