Synthesis of new DPP-4 inhibitors based on a novel tricyclic scaffold
A novel molecular scaffold has been synthesized and its synthesis and incorporation into new analogues of biologically active molecules will be discussed. A comparison of the inhibitory activity of these compounds to the known type-2 diabetes compound (sitagliptin) against dipeptidyl peptidase-4 (DP...
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Bibliographic Details
| Main Authors: |
Schwehm, Carolin,
Li, Jin,
Song, Hongmei,
Hu, Xiao,
Kellam, Barrie,
Stocks, Michael |
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| Format: | Article
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| Published: |
American Chemical Society
2015
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| Subjects: | |
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| Online Access: | https://eprints.nottingham.ac.uk/28517/
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