Genome-wide methylation and gene expression changes in newborn rats following maternal protein restriction and reversal by folic acid

A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabolic functions in the developing fetus, effectively determining susceptibility to later disease. The mechanistic basis of such programming is unclear but m...

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Bibliographic Details
Main Authors: Altobelli, Gioia, Bogdarina, Irina, Stupka, Elia, Clark, Adrian J.C., Langley-Evans, Simon C.
Format: Article
Published: Public Library of Science 2013
Online Access:https://eprints.nottingham.ac.uk/28473/