Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction
Protein interactions are increasingly appreciated as targets in small-molecule drug discovery. The interaction between the adapter protein S100A10 and its binding partner annexin A2 is a potentially important drug target. To obtain small-molecule starting points for inhibitors of this interaction, a...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Wiley-VCH Verlag
2012
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| Online Access: | https://eprints.nottingham.ac.uk/2835/ |